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Fig. 3 | Genome Biology

Fig. 3

From: Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control

Fig. 3

Genic CoRSIV-flanking regions show long-range enrichments and depletions for specific classes of transposable elements. A Using 1 kb step sizes, each plot shows significant enrichments or depletions for CpG islands (CGI) and subclasses within each of 8 classes of transposable element within 50 kb of genic CoRSIVs. Compared to control regions, CoRSIV-flanking regions show long-range depletion of CpG islands and enrichment of specific classes of LINEs and LTRs. B Compared to CoRSIVs showing a positive mQTL beta coefficient, those with negative coefficients are depleted for CpG islands and show long-range depletion of specific LINE1s and all subclasses of Alus. C The strength of mQTL associations at CoRSIVs (R2 in 4th vs. 1st quartile) is not associated with widespread differences in genomic content of transposable elements. D Compared to regions in which HM450 probes are located, CoRSIVs show short- and long-range enrichments for many subclasses of LINE1 and LTR retrotransposons

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