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Table 2 List of reference atlas available for spatial omics applications (as of March 2022). HPA Human Protein Atlas (https://www.proteinatlas.org/), HCA Human Cell Atlas (https://www.humancellatlas.org/), Tabula Sapiens (https://tabula-sapiens-portal.ds.czbiohub.org/)

From: Spatial omics technologies at multimodal and single cell/subcellular level

 

GeoMx

HPA

HCA

HCA

Tabula sapiens

 

Coverage

Project counts

Est. cell counts

Cell counts

Lung

N

Y

18

6,200,000

35,682

Kidney

Y

Y

9

4,900,000

9641

Liver

N

Y

10

5,400,000

5007

Brain

Y

Y

14

9,700,000

N/A

Skin

N

Y

12

1,500,000

9424

Colon (large intestine)

Y

Y

4

1,100,000

N/A

Rectum (large intestine)

N

Y

2

372,300

N/A

Small intestine

N

Y

3

986,700

12,467

Stomach

N

Y

3

4,600,000

N/A

Lymph node

Y

Y

3

536,700

53,275

Prostate

N

Y

3

798,900

16,375

Ovary

N

Y

3

525,100

N/A

Uterus

N

Y

3

1,000,000

7124

Heart

N

Y

8

6,200,000

11,505

Esophagus

N

Y

4

914,600

N/A

Bone marrow

N

Y

3

571,700

12,297

Bone (skeletal muscle)

N

Y

2

212,600

N/A

Adipose (fat)

N

Y

4

1,000,000

20,263

Bladder

N

Y

2

486,700

21,517

Eye

N

Y

7

4,900,000

10,650

Testis

N

Y

2

30,200

N/A

Spleen

N

N

5

4,800,000

34,004

Appendix (large intestine)

N

Y

N/A

N/A

N/A

Bile duct

N

N

1

84,375

N/A

Pancreas

Y

Y

16

5,100,000

13,497

Smooth muscle

N

Y

N/A

N/A

30,746

Nasal cavity

N

N

3

114,800

N/A

Peritoneum

N

N

N/A

N/A

N/A

Blood

N

N

28

3,000,000

50,115

Breast

N

Y

2

709,100

N/A

Large intestine

N

Y

2

482,300

13,680

Mammary gland

N

N

1

N/A

11,375

Salivary gland

N

Y

1

N/A

27,199

Thymus

N

Y

3

4,800,000

33,664

Tongue

N

N

1

N/A

15,020

Trachea

N

N

3

564,700

9522

Vasculature

N

N

1

N/A

17,071