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Fig. 7 | Genome Biology

Fig. 7

From: METTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets

Fig. 7

Analysis of overlapping datasets regulated by METTL4/6mA, lncRNA RP11-390F4.3, and HIF-1α, and a summary model. a Venn diagram shows the number of genes that was co-regulated by METTL4/6mA, lncRNA RP11-390F4.3, and HIF-1α. b KEGG analysis of the 92 co-regulated genes, in which glycolysis and HIF-1 signaling pathways are on the top of the list. c Categorization of the 92 genes shows that they mainly belonged to the main hypoxia-induced phenotypes (angiogenesis, stemness, cancer metabolism). d A model to summarize the results and the mechanisms from this report

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Genome Biology

ISSN: 1474-760X

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