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Table 1 Overview of studies compiled for meta-analysis, listing each publication by a GroupID, the method of determining half-lives, the species of origin (M: mouse, H: human), the cell type of origin, and number of samples (comma-separated when listing human and mouse, respectively)

From: The genetic and biochemical determinants of mRNA degradation rates in mammals

GroupID

Method

Species

Cell types

Samples

Reference

Akimitsu

BrU (BRIC-seq)

H

HeLa

1

[41]

Akimitsu2

BrU+4sU (Dyrec-seq)

H

HeLa

1

[42]

Bazzini

4sU (SLAM-seq), ActD

H

K562, RPE, HeLa, HEK293

4

[29]

Cramer

4sU (TT-seq)

H

K562

1

[43]

Cramer2

4sU (TT-seq)

H

K562

1

[44]

Darnell

ActD

H

HepG2

1

[38]

Dieterich

4sU

H

HEK293, MCF-7

4

[45]

Gejman

4sU

H

LCLs (7 lines)

15

[46]

He

ActD

H

HeLa

2

[36]

Jaffrey

ActD

H

HEK293

1

[47]

Marks

ActD

H

HeLa

1

[48]

Mortazavi

4sU (Long-TUC-seq)

H

GM12878

1

[49]

Oberdoerffer

BrU (BRIC-seq)

H

HeLa

1

[50]

Rinn

ActD

H

K562, H1-ESC

6

[51]

Rissland

4sU

H

HEK293

4

[27]

Shendure

4sU

H

A549

1

[52]

Rissland2

4sU, ActD, α-Amanitin

H, M

HEK293, 3T3

6, 2

[53]

Simon

4sU (TimeLapse-seq)

H, M

K562, MEF

2, 2

[54]

Zimmer

ActD

H, M

B cell, 3T3

1, 1

[55]

Ameres

4sU (SLAM-seq)

M

mESC

1

[56]

Bartel

ActD

M

3T3

1

[7]

Bartel2

5EU

M

3T3

2

[57]

Darnell

ActD

M

mESC

1

[58]

Dolken

4sU (SLAM-seq)

M

M2-10B4 (bone marrow)

1

[59]

Hanna

ActD

M

mESC, mEB

2

[60]

Hu

ActD

M

mESC (E14Tg2a)

1

[61]

Ko

ActD

M

mESC

4

[6]

Koszinowski

4sU

M

3T3

1

[62]

Mattick

ActD

M

Neuro-2a

1

[41]

Regev

4sU

M

Dendritic cells

1

[63]

Regev2

4sU

M

Dendritic cells

1

[64]

Selbach

4sU

M

3T3

2

[65]

Wilusz

ActD

M

C2C12

3

[66]