metaMIC: reference-free misassembly identification and correction of de novo metagenomic assemblies

Table 1 Performance comparison of metaMIC and MEC on four real datasets from the GAGE-B project

Species	Correction tool	Misassembled contig length	FN	TP	FP
M. abscessus	raw	1,189,973	20	\	\
	MEC	982,986	14	6	2
	metaMIC	593,741	6	14	2
V. cholerae	raw	597,777	7	\	\
	MEC	597,183	6	1	0
	metaMIC	205,644	3	4	1
R. sphaeroides	raw	135,153	2	\	\
	MEC	64,489	1	1	0
	metaMIC	0	0	2	7
B. cereus	raw	117,830	5	\	\
	MEC	56,086	4	1	0
	metaMIC	28,068	1	4	3

Misassembled contig length denotes the total number of bases in the raw misassembled contigs or the misassembled contigs that cannot be corrected by MEC or metaMIC. True positive (TP) is the number of true misassemblies identified by the error correction tool. False positive (FP) is the number of misassemblies which are actually correct but mistakenly identified as misassemblies. False negative (FN) denotes the number of true misassemblies that are not identified

ISSN: 1474-760X