Fig. 5From: Evolution and function of developmentally dynamic pseudogenes in mammalsRegulatory layer of dynamic pseudogenes. a Distribution of transcript length for dynamic and non-dynamic human pseudogenes. b Diversity of TF binding sites overlapping the promoters of protein-coding genes, lncRNAs, Iso-seq detected dynamic pseudogenes, dynamic pseudogenes, non-dynamic pseudogenes, and randomly shuffled intergenic regions in mouse. c Number of chromHMM states overlapping protein-coding genes, dynamic pseudogenes, and non-dynamic pseudogenes. d, e Roadmap ChIP-seq signal of H3K27ac and DNase I hypersensitivity (DHS) at 10-kb intervals surrounding TSSs, respectively. f Density distribution of the distance from m6A modification sites to TSSs. g Number of RNA-binding proteins (RBPs) overlapping the promoter regions. h Circos plot showing genome-wide pseudogene–protein-coding gene contacts based on their pairwise-interacting RNAs. The first track (shown by coding) indicates protein-coding genes, and second track (shown by pseudo) represents pseudogenes. Green line, interaction between protein-coding genes and non-dynamic pseudogenes; grey line, interaction between protein-coding genes and dynamic pseudogenes. i GO enrichment (biological processes) of protein-coding genes significantly correlated with dynamic and non-dynamic pseudogenes. j Proportions of four types of genes interacting with mRNAsBack to article page