From: ReadZS detects cell type-specific and developmentally regulated RNA processing programs in single-cell RNA-seq
Method
Sierra [16]
MAAPER [17]
scDaPars [15]
ReadZS
Single-cell resolved (no pseudobulking)
No
Yes
Imputation-free
Does not require gene annotations
Does not require peak calling
Can be used with continuous metadata, e.g., pseudotime