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Fig. 3 | Genome Biology

Fig. 3

From: ReadZS detects cell type-specific and developmentally regulated RNA processing programs in single-cell RNA-seq

Fig. 3

ReadZS detects regulated RNAP in Arabidopsis root cell differentiation. A The ReadZS detects a global trend of 3′ UTR lengthening in the pseudotime trajectory by cell type of Arabidopsis root cells, as indicated by significant positive correlations between ReadZS and pseudotime. The trend is consistent whether the ReadZS was calculated for each 1kb genomic window (left) or for each gene (right). This analysis was performed for each cell type in libraries sc_1, sc_9_at, sc_10_at, and sc_11, and all the correlation values are aggregated in the histogram. B Binned histogram of read positions from genomic windows in Arabidopsis root with significant correlation between ReadZS and pseudotime: in atrichoblasts, genomic window overlapping the gene At5g10430 (Spearman’s correlation = 0.658, Bonferroni-corrected p-value < 0.0001), from library sc_9_at. C Binned histogram of read positions from genomic windows in Arabidopsis root with significant correlation between ReadZS and pseudotime: in trichoblasts, genomic window overlapping the gene At5g44020 (Spearman’s correlation = 0.620 Bonferroni-corrected p-value < 0.0001), from library sc_11

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