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Fig. 5 | Genome Biology

Fig. 5

From: MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution

Fig. 5

Inferred phylogeny for single-cell data with 1023 cells. Inferred phylogeny and allele-specific copy-number profiles for patient TN2 from Minussi et al. [46]. The diploid and most recent common ancestor to all cells are marked with green and blue circles, respectively. We manually selected clades from the phylogeny to match the superclones and subclones of the original publication. These are marked next to the tree in the colors of the original publication and with horizontal lines. The structure of the tree corresponds very clearly with distinct features of the copy-number profiles and matches the clonal structure derived in the original publication. Selected synapomorphies of the clone structure are highlighted with a yellow border and annotated on the figure

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