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Fig. 2 | Genome Biology

Fig. 2

From: A quantitative metric of pioneer activity reveals that HNF4A has stronger in vivo pioneer activity than FOXA1

Fig. 2

HNF4A has stronger pioneer activity than FOXA1. A Distributions of dox50 estimates extracted from binding curves at FOXA1-accessible binding sites (n = 1930), FOXA1 inaccessible binding sites (n = 9627), HNF4A accessible binding sites (n = 2135), and HNF4A inaccessible binding sites (n = 3805). B, C Distributions from FOXA1 (B) and HNF4A (C) shown in histogram form. D Same plot as A but each genomic binding site is binned by whether the site has < 2, ≥ 2 but < 4, or ≥ 4 motifs as called by FIMO (p = 1e−3)

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