Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes

Table 3 Estimates of PAR1 population genetic parameters for human (HUM) and great ape populations

	𝜌	𝜋	𝜃_PAR (𝜃_A)	Tajima’s D	N_e	𝜇 (PG)	𝜇 (PY)	B
HUM	-	0.0025	0.0025 (0.0009)	− 0.0541	-	-	-	0.6745
PTE	12,922	0.0024	0.0026 (0.0013)	− 0.2500	14,138	4.31 × 10⁻⁸	1.72 × 10⁻⁹	0.6801
PTS	16,141	0.0023	0.0026 (0.0016)	− 0.3273	17,661	3.31 × 10⁻⁸	1.32 × 10⁻⁹	0.6064
PTT	32,855	0.0028	0.0039 (0.0023)	− 1.0783	35,948	1.97 × 10⁻⁸	0.79 × 10⁻⁹	0.8125
PTV	9,136	0.0013	0.0014 (0.0008)	− 0.2132	9,996	3.33 × 10⁻⁸	1.33 × 10⁻⁹	0.7302
PPA	15,293	0.0011	0.0014 (0.0005)	− 0.7477	16,732	1.70 × 10⁻⁸	0.68 × 10⁻⁹	0.7704
GGG	12,584	0.0023	0.0022 (0.0016)	0.1314	13,769	4.10 × 10⁻⁸	2.16 × 10⁻⁹	0.7640
PAB	11,901	0.0038	0.0037 (0.0019)	0.1374	13,021	7.26 × 10⁻⁸	2.79 × 10⁻⁹	0.6531
PPY	13,728	0.0027	0.0023 (0.0013)	0.6627	15,020	4.48 × 10⁻⁸	1.72 × 10⁻⁹	0.4962

𝜌 = 4N_er of the whole PAR1 region, as measured by LDhat
𝜋 = 4N_e𝜇; average pairwise diversity estimator of PAR1
𝜃 = 4N_e𝜇; Watterson’s diversity estimator (𝜃_PAR = PAR1 𝜃; 𝜃_A = autosomal 𝜃)
N_e = effective size of the population
𝜇 = per site and per generation (PG), or per year (PY) mutation rate
B = 4N_eb; strength of GC-biased gene conversion in PAR1
PTE P. troglodytes ellioti, PTS P. troglodytes schweinfurthii, PTT P. troglodytes troglodytes, PTV P. troglodytes verus, PPA P. paniscus, GGG G. gorilla gorilla, PAB P. abelii, PPY P. pygmaeus

ISSN: 1474-760X