Fig. 1

PAR1 phylogenetic tree and sequence alignment between great ape species. The total alignment consists of 620,054 syntenic sites of which 239,799 are putatively neutral (highlighted in yellow). As indicated by letters in the tree diagram, the species are as follows, from top to bottom: human (H), chimpanzee (C), gorilla (G), orangutan (O) and macaque (M). The number associated with each branch label is the divergence rate ratio with respect to the human rate (presented in parentheses), since the branching of the great ape ancestor (red point)