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Fig. 5 | Genome Biology

Fig. 5

From: Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses

Fig. 5

HU treatment generates a distinctive pattern of CNAs. A Replication timing of HU CNAs. B Proximity to large genes. C Proportion of hCNAs found within 1 Mb of a large gene. D Gene expression in 2 sMb windows around hCNA breakpoints. E Proximity of control sites or hCNAs to RPE1-specific CFS or all human ERFS. Statistical tests compare all hCNA classes to in silico control CNAs using a one-way ANOVA Kruskal-Wallis test with post hoc Dunn’s correction

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