Fig. 3

Plasmid sharing among bacteria within and between hosts. A Plasmid similarity network as visualized by MobMess. Each network node indicates a putative plasmid predicted from by PlasX, and each edge indicates shared sequence identity with another plasmid. Node fill colors indicate the host ape individual from which the plasmid was sequenced, and node border colors indicate whether the plasmid sequence was determined to be linear or circular. Focal plasmid groups are indicated by a white border. B Focal plasmid group with sequence similarity shared among five host individuals. Node colors as in A. Right panel shows plasmid predicted gene content, with colored regions between alignments indicating alignment identity between plasmids; alignment identity indicated by the color bar at the right. C Focal plasmid group with sequence similarity shared among two P. paniscus host individuals. Alignments have higher sequence identity within individuals than between. D Focal plasmid group with sequence similarity shared among P. paniscus and P. t. troglodytes individual. Some plasmids show a high degree of sequence synteny and identity between individuals (e.g., between plasmids 1 and 2, or 3 and 5), while others show sequence insertions and lower identity to related plasmids within the same individual (e.g., between plasmids 2 and 3)