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Fig. 3 | Genome Biology

Fig. 3

From: Whole-genome sequencing reveals the genetic mechanisms of domestication in classical inbred mice

Fig. 3

Proportion of differently expressed genes increased in the 339 PSGs. a Ratio of differently expressed genes in the hypothalamus, hippocampus, frontal lobe, heart, liver, and lung. Genes with p adjustment < 0.05 and FPKM > 1 are considered differently expressed. b Elevation of differently expressed gene ratio in the 339 PSGs compared with all genes. The left vertical axis corresponds to the columns, indicating the increased part of differently expressed gene ratio in the 339 PSGs compared with all genes. The right vertical axis corresponds to the dot and line, indicating the increased percentages of differently expressed gene ratio in the 339 PSGs compared with all genes. c The heatmap indicates the expression changes of the 56 common differently expressed genes (merged from hippocampus and frontal lobe) in the hippocampus. d The qPCR validation for the gene expression of Kcnd2 (upper panel) and Sebox (bottom panel) between classical inbred (n = 5 in each group) and wild (n = 5 in each group) mice. Each circle indicates one individual mouse, and error bars are standard error of mean (SEM). * indicates p < 0.05

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