Fig. 3
From: Genomics and epigenetics guided identification of tissue-specific genomic safe harbors
Experimental validation of GSHs in HUDEP2 cells. a PCA plot showing the RNA-seq data for all tested cell lines. b–d Volcano plots showing differential expressed genes (DEGs) in a blood GSH (BLD_GSH_10), non-GSH MEI (MEI_chr3_3707_INS) and AAVS1. Common: DEGs share by more than two cell lines. Same TAD: genes within the same TAD of the GFP integration site; +/− TAD: genes in the TADs flanking to the GFP integration site