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Fig. 2 | Genome Biology

Fig. 2

From: Abnormal molecular signatures of inflammation, energy metabolism, and vesicle biology in human Huntington disease peripheral tissues

Fig. 2

Proteomics analysis of adipose, muscle, and skin samples. A–C Volcano plots of proteomics data from adipose (A), muscle (B), and skin (C) tissue samples. Pair-wise comparisons of pre-HD and early-HD against controls and early-HD against pre-HD are shown. The x-axis is the log2(expression) change and y-axis -lg10(p-value) from the ROTS analysis. The red horizontal line highlights the p-value of -lg10(3) = 0.001. Proteins with a significance value of less than 0.001 are depicted and proteins with an adjusted p-value (ROTS FDR) of < 0.05 are shown in bold. Upregulated protein are shown in red, downregulated proteins in blue. See also Additional files 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 and 19 for full data

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Genome Biology

ISSN: 1474-760X

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