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Fig. 1 | Genome Biology

Fig. 1

From: Prediction of evolutionary constraint by genomic annotations improves functional prioritization of genomic variants in maize

Fig. 1

Distribution of rejected substitution (RS) scores by category of DNA bases. RS scores, which integrate information about conservation (1 − Substitution rate) and MSA depth (Tree size), were calculated by gerp++ [4] as previously described [14]. Monomorphic sites: sites with no observed polymorphism within maize. SNPs: observed polymorphisms in Hapmap 3.2.1, a representative panel of inbred lines in maize [15]. SNPs in hybrid panels: subset of SNPs which are observed in two panels of hybrid crosses between inbred lines and testers [16]

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