Fig. 6
From: Comparative transcriptome in large-scale human and cattle populations
Heatmap of heritability enrichments of 46 human complex traits in transcriptionally conserved and diverged genes. Heritability enrichments obtained from LDSC for 46 human complex traits in transcriptionally diverged and conserved genes between humans and cattle (“Methods”). All orthologous genes are ranked (from largest to smallest) based on –log10p obtained from the differential gene expression analysis in each of 20 tissues between humans and cattle. The top and last 10% of genes are considered as transcriptionally diverged and conserved genes in each tissue, respectively. The enrichment is scaled to have mean of zero and variance of one by traits. “*” represents the adjusted P-value (FDR) < 0.05. Traits and tissues are clustered using the Hierarchical clustering method