Fig. 3
From: Survey of the binding preferences of RNA-binding proteins to RNA editing events
Preferences of RBPs to specific RNA editing events. A Statistical analysis of the differential RNA editing levels in eCLIP vs. whole-cell RNA-seq in K562 (green) and HepG2 (brown) cells. Each dot represents a single RNA editing site. The X-axis shows the difference in the editing levels, and the Y-axis shows the significance level. B Overall statistics of the numbers of RBP-associated editing sites for the 150 RBPs in K562 and HepG2 cells. C The numbers of RNA editing events favored or disfavored by the top 9 RBPs with the largest numbers of RBP-associated editing sites. D EMSA assays showing the shifted RNA bands upon preincubation with the two proteins HNRNPC and ILF3, respectively. E Scatter plots of the UPF1- and DROSHA-associated editing sites, showing their editing levels in the eCLIP data (X-axis) and in the whole-cell RNA-seq data (Y-axis). The numbers of sites falling in each triangle domain are provided on the plots