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Fig. 5. | Genome Biology

Fig. 5.

From: Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia

Fig. 5.

KMT2A fusion complex rearrangement related genes (CRGs) are colocalized with KMT2A and partner genes better than control. A An example of complex rearrangements (CRs) involving KMT2A, AFF1, and PDE6C. B Comparisons of CR tightness between CRGs and control for three fusions KMT2A-AFF1, KMT2A-MLLT3, and KMT2A-MLLT10. The smaller the CR tightness score, the closer the genes. C CRGs are more often colocalized with KMT2A and fusion partners simultaneously than control genes; the y-axis shows the percentage of genes that are co-localized with KMT2A and fusion partners simultaneously

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Genome Biology

ISSN: 1474-760X

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