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Fig. 1 | Genome Biology

Fig. 1

From: BASS: multi-scale and multi-sample analysis enables accurate cell type clustering and spatial domain detection in spatial transcriptomic studies

Fig. 1

Workflow of BASS. BASS performs multi-scale and multi-sample analysis for accurate cell type clustering and spatial domain detection in spatial transcriptomics. BASS takes input of the gene expression matrix and spatial location information from multiple tissue sections and models both information in a hierarchical Bayesian framework. In the analysis, BASS treats the cell type label (c) and the spatial domain label (z) for each cell on the tissue as latent/hidden variables and infers them through an efficient inference algorithm. After analysis, BASS provides the inferred cell type cluster labels, the spatial domain labels, and the cell type proportions inside each spatial domain as outputs

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Genome Biology

ISSN: 1474-760X

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