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Fig. 4 | Genome Biology

Fig. 4

From: Integration of single-cell multi-omics data by regression analysis on unpaired observations

Fig. 4

UnpairReg enhances cell type identification. A UMAP of the predicted gene expression from UnpairReg. Color in A to E indicates the ground truth label of PBMC data. The circled cell types from left to right are non-classical monocytes, plasmacytoid DC, memory B cells, and naïve B cells, respectively. B UMAP of the gene expression predicted by GAS. C UMAP of observed gene expression from the multiome data. D Silhouette index (SI) of cells based on predicted gene expression from UnpairReg and GAS. p-value is the significant level of the one-sample t-test. E SI of cells based on UnpairReg-predicted gene expression and the observed multiome gene expression data. p-value is the same as D

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