Fig. 1
From: Integration of single-cell multi-omics data by regression analysis on unpaired observations
Schematic overview of UnpairReg model. A Schematic of the linear regression model based on paired chromatin accessibility and gene expression data. Gene expression level and chromatin accessibility are observed in the same cell. TG1 and TG2 are from two different genomic locations. RE1-TG1 regulation, RE5-TG2 regulation, TG1-TG2 correlation, and RE1-RE5 correlation are observed by data. B Schematic of the UnpairReg model based on unpaired data. Gene expression level is observed only for cell 1 to cell 5, while chromatin accessibility is observed for cell 6 to cell 10. TG1-TG2 correlation and RE1-RE5 correlation are observed in this data but no other significant correlation between REs and TGs. So, we infer RE1-TG1 regulation and RE5-TG2 regulation