Fig. 1
From: scSTEM: clustering pseudotime ordered single-cell data
Flowchart of scSTEM pipeline. A The flowchart of scSTEM gene clustering. Colored solid circles represent cells mapped to different key segments of a trajectory tree. Aggregation of expressions are performed for each key segment. The resulted matrix (rows as genes and column as key segments) will be used as input for STEM to perform gene clustering. B Comparison function enables comparison of clustering results from different trajectory paths. This will identify clusters having similar genes but showing different/similar temporal expression patterns