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Fig. 5 | Genome Biology

Fig. 5

From: Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions

Fig. 5

Tissue-specific network rewiring. A A network diagram of interaction rewiring of CPD in glioma cell lines. B IGF1R-CPD loss of interaction was detected in glioma cell lines. C CPD-FURIN interaction was correlated regardless of tissue type. D CPD is correlated with MET instead of IGF1R in glioma cell lines. E Abundance of proMET and mature MET receptor in three glioma cell lines, in response to CPD knockout or negative control (ADH7ko). F Densitometry of Western blots shows ratio of proMET to MET more than doubles in CPD−/− cells

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