Fig. 2From: Open problems in human trait geneticsIdentifying causal variants in the presence of linkage disequilibrium. A A single causal variant is in linkage disequilibrium with other nearby variants. As a result, variants that are correlated with the causal variant also obtain significant p-values even though they are not causal. B Combining GWAS summary statistics from three different ancestry groups, each exhibiting a different linkage disequilibrium pattern, to fine-map the results. By assuming that only one of the variants is causal, it can be recovered with high confidenceBack to article page