Fig. 2
From: Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection
Performance of simulated and sub-sampled input data. a Log2-fold change of AUPRC values obtained from DCSsim simulated and DCSsub sub-sampled data. Values >0 indicate a better performance based on AUPRC for simulated data and <0 indicates a higher AUPRC for sub-sampled input. The overall difference for all DCS tools is shown on the left (bar with gray background). Tools were ordered by their median log2-fold change. b Comparison of AUPRC values of simulated and sub-sampled data for peak-dependent (n = 431) vs. peak-independent (n = 1363) DCS tools. P-value two-sided Wilcoxon rank sum test. Box plot limits, 25% and 75% quantiles; center line, median; whiskers, 1.5× interquartile range