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Fig. 3 | Genome Biology

Fig. 3

From: Identifying common transcriptome signatures of cancer by interpreting deep learning models

Fig. 3

Fraction of genes with driver mutations (A), frequency of passenger mutations (B), structural variants (C), amplification events (D), or deletion events (E) in the TCGA cohort. The analysis was performed on the following sets of genes: COSMIC oncogenes (yellow), COSMIC tumor-suppressor genes (TSGs, green), genes with high positive (“protein-coding positive,” red), high negative (“protein-coding negative,” blue), or neutral attribution values by expression (“protein-coding neutral,” gray) or genes with splice junctions with high (“splicing high,” light red) or neutral (“splicing neutral,” light gray) attribution values in our models. p-values were calculated using a one-way ANOVA with Tukey post hoc tests

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