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Fig. 1 | Genome Biology

Fig. 1

From: Explainable multiview framework for dissecting spatial relationships from highly multiplexed data

Fig. 1

MISTy: An explainable multiview framework for modeling intercellular interactions from highly multiplexed spatial data. MISTy models marker relationships coming from different spatial views: intrinsic (intraview), local niche view (juxtaview), the broader, tissue view (paraview), or others, based directly on marker expressions or derived typology or functional characterizations of the data. At output, A MISTy extracts information about the contribution of different views to the expression of markers in each spatial unit. B MISTy also estimates the markers’ interactions coming from each view that explains those contributions. C These results can be described qualitatively as communities of interacting markers for each view

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