Fig. 6

Predicted riboSNitches and non-riboSNitches in the population of 879 Eurasian accessions do not differ in their chromosomal densities and allelic frequencies. A, B The genome-wide SNV density, expressed as number of variants per 100,000 nt, for A 1,038,347 riboSNitches and B 2,791,917 non-riboSNitches. The genome-wide distribution of riboSNitches and non-riboSNitches is not significantly different (Wilcoxon P value > 0.05). Arrowheads depict the centromeric regions with lower SNV densities. C The average SNPfold correlation coefficient does not differ significantly among rare, low-frequency, and common variants (Wilcoxon P value > 0.05). D Among rare variants, at the lowest possible allele frequency (MAC = 1), the ratio of riboSNitches to non-riboSNitches is higher than the expected ratio for rare SNVs (post hoc tests following a chi-square, using the Bonferroni adjustment, P value < 0.001). Significant differences also occur in the opposite direction within rare variants (MAC = 4; post hoc tests following a chi-square, using the Bonferroni adjustment, P value < 0.05). E Table summarizing the frequencies and ratios of candidate riboSNitches and non-riboSNitches