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Fig. 2 | Genome Biology

Fig. 2

From: Exaggerated false positives by popular differential expression methods when analyzing human population samples

Fig. 2

The Wilcoxon rank-sum test has the best FDR control and power on heart left ventricle vs. atrial appendage GTEx datasets with semi-synthetic ground truths. A The FDR control (left panel), power (middle panel) given the claimed FDRs, and power given the actual FDRs (right panel) under a range of FDR thresholds from 0.001 to 5%. B The FDR control (left), power given the claimed FDRs (middle), and power given the actual FDRs (right) for a range of per-condition sample sizes from 2 to 100, under FDR thresholds 10% (top panels) and 1% (bottom panels). The claimed FDRs, actual FDRs, and power were all calculated as the averages of 50 randomly down-sampled datasets

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