Fig. 3From: Meta-analysis defines predominant shared microbial responses in various diseases and a specific inflammatory bowel disease signalNon-specific microbial signal shared across diseases. A Heatmap showing 128 non-specific ASVs identified by applying a binomial test on the ratios of the 731 ASVs across all diseases (FDR < 0.1). Columns are disease cohorts, and rows represent the non-specific ASVs that were significantly changed in at least four different diseases, with colors representing the NRMD. Red and blue indicate higher or lower abundance in disease respectively, while white indicates ASVs not present in the study. B Non-specific ASVs were separated to two groups; those lower in disease (76% of non-specific ASVs, left column), and those that are higher in disease (24% of non-specific ASVs, right column). The fraction of bacteria from each of these groups is shown for three taxonomic levels as indicated: phylum, order, and classBack to article page