Fig. 1

Taxonomic composition of the vaginal microbiota of 39 women at up to five timepoints as assessed by shotgun metagenomics (n=194, A). Relative contribution of each species to the metatranscriptome of the corresponding samples (n=180, B). Both estimates were derived using VIRGO mapping results and were corrected for gene length. Samples were sorted in the same order in the two datasets. Gaps indicate the fourteen samples for which no corresponding metatranscriptomic data were available. Communities were assigned to CSTs based on their taxonomic composition using VALENCIA [9] according to the following scheme: CST I–L. crispatus dominated, CST II–L. gasseri dominated, CST III–L. iners dominated, and CST V–L. jensenii dominated) and CST IV. Separate plots that display the longitudinal data series for each individual subject can be found in Supplementary File 1