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Table 3 Numbers of significant distal HVRs identified by applying different parameter estimation methods with various cutoffs of the BH-adjusted p-value

From: HyperChIP: identification of hypervariable signals across ChIP-seq or ATAC-seq samples

Parameter estimation Data set Number of significant distal HVRs
0.01 0.05 0.1
Original H3K27ac ChIP-seq 2 8 12
ATAC-seq 0 3 4
Pol II ChIP-seq 0 0 0
Lower 10% + winsorization H3K27ac ChIP-seq 289 1372 2621
ATAC-seq 3124 6830 10,234
Pol II ChIP-seq 602 1400 2122