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Fig. 2 | Genome Biology

Fig. 2

From: Evaluating statistical approaches to define clonal origin of tumours using bulk DNA sequencing: context is everything

Fig. 2

Summary of evolutionary models. This figure depicts different aspects of cancer evolution and is adapted from [20, 21]. In parallel evolution, the tumour arises from a single cancer-initiating cell (at the base of the trunk) in the same patient, whereas in convergent evolution, phenotypically similar tumours arise from different cancer-initiating cells in the same or different patients. Purple circles depict tumour subclones with a similar phenotype

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Genome Biology

ISSN: 1474-760X

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