Fig. 3

Prediction accuracy of predicted transcriptome risk scores (PTRS). a Prediction accuracy, measured by partial \(\widetilde {R}^{2}\), of PTRS (on y-axis) compared to the accuracy of PRS (on x-axis). b Prediction performance is shown on x-axis and heritability (for PRS) and proportion of variance explained (for PTRS) are shown on y-axis. c Prediction accuracy of MESA AFHI PTRS vs MESA EUR PTRS in the 4 target populations