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Fig. 2 | Genome Biology

Fig. 2

From: Strainline: full-length de novo viral haplotype reconstruction from noisy long reads

Fig. 2

The schematic diagram for the sequencing error correction procedure of raw reads. In the top region, the bold solid line denotes the target raw read i, and the overlapping reads of the target read i are drawn dashed outside of the read alignment pile and solid inside of it. The pink fork represents the sequencing error, i.e. mismatch, insertion or deletion. The read alignment pile is split into k small windows, representing as Win 1, Win 2,... Win k. DBG is short for de Bruijn Graph. Window consensus refers to the highest scoring sequences (see main text for explanations) through the DBGs of small windows over the read alignment pile. The region filled with gray rhombus between two window consensus denotes the overlap between them (30bp). We perform the error correction step for each raw read

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