Fig. 4

Relationships between 4acC and 5mC in the Arabidopsis genome. a 4acC distribution in Arabidopsis chromosome 1. The top panel shows the average 4acC levels per 100-kb bin. The middle panel shows the average 5mC levels at CG, CHG, and CHH sites, and the bottom panel shows the densities of genes and TEs. b The average levels of 5mC (CG, CHG, and CHH) in 4acC peaks with 1 kb upstream and downstream flanking regions and random regions. c 4acC profiles of met1 and rdd mutants in gene regions. The 1 kb upstream and downstream flanking coding regions were aligned for all genes. TSS, transcription start site; TES, transcription end site. d Overlaps of 4acC peaks among WT, met1 mutant and rdd mutant plants. e, f Percentages of DARs that overlapped with DMRs in met1 (e) and rdd (f) mutants. The p values in e and f were calculated for significant differences between two groups by Fisher’s exact test. g Fold changes in mCG levels in DARs and randomly selected regions between the met1 mutant and WT plants. h–j Fold changes in mCG (h), mCHG (i), and mCHH (j) levels in DARs and randomly selected regions between the rdd mutant and WT plants