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Table 1 Description of datasets

From: sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies

Dataset

# Samples

# SNPs

Adjustments

Phenotype

SHIPa

3699

5M

Sex, age, smoking status, daily alcohol consumption

SLAb, dichotomous (75th percentile, 934 cases, 2765 controls)

    

SLA, quantitative, Mean ±SDc 1.23 ±0.3

COPDGened

5343

600K

Sex, age, smoking status, pack years of smoking

COPDe, dichotomous, (2811 cases, 2532 controls)

    

FEV1f, quantitative, Mean ±SD 2.993 ±0.635

FinnGen

135,615

1M

Sex and age

Hypertension, dichotomous, (34,257 cases, 101,358 controls)

  1. aStudy of Health in Pomerania
  2. bSerum lipase activity
  3. cStandard deviation
  4. dGenetic Epidemiology of chronic obstructive pulmonary disease
  5. eChronic obstructive pulmonary disease
  6. fForced expiratory volume in one second