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Fig. 2 | Genome Biology

Fig. 2

From: CIDER: an interpretable meta-clustering framework for single-cell RNA-seq data integration and evaluation

Fig. 2

CIDER accurately identifies cross-batch populations. A t-SNE plot shows the nine initial clusters from three batches of the simulated dataset (Dataset 2). Cells are colored by initial clusters. B The graph network shows the similarity among initial clusters. Vertexes represent initial clusters, colored by populations. The width of edges represents the similarity levels. C Distribution of ARIpopulation for 20 replicates of simulated data across integration workflows and clustering algorithms. The x-axis denotes the workflow performance by calculating ARIs between cell populations and clustering results, and the y-axis denotes clustering and integration workflows. The whiskers from left to right in the boxplot represent the first quartile, the median, and the third quartile. D, E Distribution of 1-ARIbatch (D) and runtime (E) for 20 replicates of simulated data across integration workflows and clustering algorithms

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