Fig. 3
From: Cobolt: integrative analysis of multimodal single-cell sequencing data
The UMAP visualization of A, B the mouse cortex integration and C, D the 10X PBMC integration. Cells are colored in A, C by dataset of origin, in B known cell type annotation of [31], and in D by our de novo clustering and annotated based on gene markers. For the mouse cortex integration, both the MOp scRNA-seq and the MOp scATAC-seq contain a substantial fraction of cells labeled “unannotated” by the authors of the data and that do not map to known cell types. The cell type abbreviation largely follows the data paper [31]: astrocytes (Astro), caudal ganglionic eminence interneurons (CGE), endothelial cells (Endo), layer 2 to layer 6 (L2-6), intratelencephalic neurons (IT), pyramidal tracts (PT), corticothalamic neurons (CT), L6b excitatory neurons (L6b), microglial cells (MGC), near-projecting excitatory neurons (NP), oligodendrocytes (Oligo), oligodendrocyte precursors (OPC), smooth muscle cells (SMC), and medial ganglionic eminence interneurons subclasses based on marker genes (Sst, Pvalb). For the 10X PBMC integration, the following abbreviations are observed: dendritic cell (DC), plasmacytoid dendritic cells (pDC), monocytes (mono), and natural killer cells (NK)