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Fig. 2 | Genome Biology

Fig. 2

From: Single-cell characterization of CRISPR-modified transcript isoforms with nanopore sequencing

Fig. 2

a Overview of single-cell CRISPR screen integrated with long-read sequencing. b IGV view of SRSF5-1 target site for cells containing different gRNA sequences. Reads from cells with SRSF5-1 gRNA show CRISPR-induced insertion (purple) and deletion (black line). CRISPR cut site and analysis window for statistical analysis are shown. c The percentage of mutated reads per each cell are shown as a box plot

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