Table 2 Enrichment of the pathway “Dilated cardiomyopathy (DCM)” from KEGG for the exons differentially used in DCM patients. The table shows the most significant genes (p value< 0.05) (see the “Methods” section)
Differentially spliced genes | DCM associated | Percentage of affected edges associated with DCM | P value | Affected binding (edges) associated with DCM |
|---|---|---|---|---|
MYO19 | No | 6/51 | 0.000002 | MYL2, TPM4, TPM3, TPM2, TPM1, ACTG |
OBSCN | No | 1/2 | 0.014 | TTN |
USP49 | No | 1/4 | 0.028 | PRKACA |
CACNA1C | Yes | 1/4 | 0.028 | RYR2 |