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Fig. 3 | Genome Biology

Fig. 3

From: ATRX regulates glial identity and the tumor microenvironment in IDH-mutant glioma

Fig. 3

Differences in immune-cell phenotypes, paracrine signals, and upstream transcription factors between IDH-A and IDH-O. A Percentages of monocytic-lineage cells found in IDH-A vs. IDH-O scRNA-seq data, and t-test. B Differential expression test via MAST for monocytic-lineage cells from scRNA-seq of IDH-A and IDH-O specimens. C Ligand/agonist expression in neoplastic-cell scRNA-seq from IDH-A and IDH-O specimens (top) paired to expression of the corresponding receptors in monocytic-lineage cells (bottom)

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