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Fig. 6 | Genome Biology

Fig. 6

From: Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation

Fig. 6

Example of a shared apaQTL in the gene DDX58 defined by 3′-Seq and shared by QAPA run with Iso-Seq or 3′-Seq PAS site annotations. We highlight a gene track displaying read coverage and PAS sites. The gray vertical track directly below rs7029002 represents the position of the strongest apaQTL SNP, and the surrounding gray track represents the most strongly affected PAS site. PAUs for every PAS site were stratified by genotype, as shown on the right, in which individuals with the G allele have increased PAU of the highlighted, gray PAS site. The bottom highlights boxplots of the PAU at this PAS site, stratified by genotype and APA detection method

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