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Fig. 1 | Genome Biology

Fig. 1

From: Systematic functional interrogation of human pseudogenes using CRISPRi

Fig. 1

An integrated computational pipeline for designing CRISPRi sgRNA library to screen for functional human pseudogenes and parent genes. A A workflow of the sgRNA library design for pseudogene-focused CRISPRi screen. B The number of sgRNAs targeting pseudogene, parent genes, and positive and negative control sgRNAs that were included in the screen. C The pie chart showing the percentage of different types of pseuodgenes included in the screen. D The distribution of the number of pseudogenes per parent gene that were included in the screen

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