Table 1 Identified risk loci for RA with less than three credible SNPs and the cell type in which they are active

4

chr1

10

0.53

0.94

1

1

0

0

FLS

rs4839319, rs4839318, rs77227025

5

chr1

2

0.91

0.99

1

0

0

0

B CELL

rs6679677, rs2476601

7

chr1

10

0.25

0.62

1

0

0

0

NONE

rs624988, rs771587, rs12137270, rs12405671, rs11586238

10

chr2

9

0.21

0.59

1

2

3

2

ALL

rs10175798, rs10173253, rs906868, rs7579944, rs1355208

17

chr2

4

0.43

0.92

1

0

2

0

T CELL

rs231724, rs231723, rs231775

20

chr3

13

0.34

0.82

1

4

2

3

ALL

rs73081554, rs185407974, rs180977001, rs35677470, rs114584537

24

chr5

1

1

1

1

0

1

0

T CELL

rs7731626

29

chr6

8

0.23

0.67

1

0

0

0

NONE

rs17264332, rs11757201, rs6920220, rs6927172

30

chr6

15

0.42

0.86

1

2

5

3

NONE

rs58721818, rs61117627

32

chr6

9

0.32

0.71

1

0

5

0

T CELL, B CELL

rs1571878, rs3093017, rs10946216

40

chr9

3

0.37

0.98

1

0

0

0

NONE

rs11574914, rs2812378, rs10972201

42

chr10

6

0.73

0.87

1

0

0

0

T CELL

rs706778, rs10795791

44

chr10

10

0.21

0.49

1

0

10

0

T CELL

rs537544, rs568727, rs570613 , rs570730, rs7897792

46

chr10

10

0.37

0.73

1

9

1

0

ALL

rs12764378, rs71508903, rs77509998

60

chr15

5

0.26

0.74

1

0

0

0

NONE

rs919053, rs8026898, rs7170107, rs16953656, rs8043362

62

chr16

9

0.29

0.82

1

0

0

0

B CELL

rs13330176, rs2139492, rs2139493

66

chr19

2

0.6

1

1

0

0

0

NONE

rs74956615, rs34536443

70

chr21

19

0.56

0.93

1

3

1

0

FLS

rs8133843, rs8129030, rs9979383

73

chr22

9

0.29

0.74

1

0

0

2

B CELL

rs2069235, rs909685, rs9611155

1

chr1

81

0.29

0.38

2

1

1

1

NONE

rs187786174, rs60733400, rs876938

2

chr1

13

0.29

0.52

2

0

0

0

NONE

rs2240336, rs12737739, rs13375202

3

chr1

36

0.43

0.51

2

1

0

0

FLS

rs28411352, rs28489009, rs2306627

6

chr1

29

0.22

0.42

2

0

2

4

B CELL

rs1217404, rs2476604, rs1217420

11

chr2

13

0.18

0.4

2

1

1

1

ALL

rs34695944, rs56095903, rs67574266, rs13031237, rs13031721

13

chr2

17

0.27

0.63

2

0

0

1

NONE

rs9653442, rs6712515, rs11676922, rs1160542, rs10865035

18

chr3

63

0.27

0.55

2

0

0

0

NONE

rs4452313, rs4416363 , rs7617779

19

chr3

11

0.21

0.48

2

1

1

0

T CELL, B CELL

rs9310852, rs4680838, rs9880772, rs1353286

22

chr4

49

0.2

0.29

2

0

0

0

NONE

rs7660626, rs13142500, rs6831973

31

chr6

13

0.17

0.49

2

0

2

2

B CELL

rs2451258, rs2485363, rs654690 , rs1994564, rs212389

33

chr7

47

0.24

0.47

2

3

1

2

ALL

rs186735625, rs57585717, rs2158624

36

chr8

20

0.08

0.23

2

3

1

0

FLS, B CELL

rs2736337

38

chr8

11

0.15

0.39

2

1

0

0

FLS

rs678347, rs507201, rs657425

43

chr10

17

0.27

0.45

2

0

3

2

T CELL, B CELL

rs947474, rs10796038, rs10796040

45

chr10

44

0.36

0.54

2

0

2

0

NONE

rs12413578, rs144536148, rs186856025

47

chr11

59

0.47

0.53

2

4

2

5

NONE

rs12574838, rs331463

51

chr11

17

0.12

0.36

2

2

8

0

NONE

rs4936059, rs11221402, rs7106876

54

chr12

22

0.22

0.51

2

0

1

1

T CELL, B CELL

rs10774624, rs3184504, rs7310615

56

chr14

12

0.13

0.37

2

3

2

0

ALL

rs1950897, rs911263, rs1885013, rs2104047, rs3784099

57

chr14

21

0.22

0.45

2

7

10

6

ALL

rs7146217, rs36045050, rs11158764

58

chr15

17

0.25

0.48

2

1

12

2

T CELL, B CELL

rs8032939, rs8043085, rs4924273

61

chr16

18

0.08

0.23

2

0

0

0

NONE

rs11075010, rs1579258, rs4584833

63

chr17

39

0.49

0.67

2

0

0

6

NONE

rs7224929, rs58483057, rs2071456

67

chr20

11

0.32

0.59

2

1

1

1

ALL

rs4239702, rs4810485, rs1883832

71

chr21

37

0.32

0.6

2

0

26

0

T CELL

rs1893592, rs225433, rs11203203

72

chr22

103

0.24

0.26

2

9

20

22

T CELL, B CELL

rs11089637, rs11089620, rs5754387