Fig. 5

ExOrthist compare_exon_sets module. a Schematic representation of the inputs required by the compare_exon_sets module and of the provided output. For a given query regulated exon (red): “Gene ortholog,” the query exon belongs to a gene that has orthologs in the target species; “Exon ortholog,” the target exon has at least one valid exon ortholog as defined by ExOrthist in the target species (referred to as Genome conservation or G-conservation); “Regulated exons,” both the query exon and a target exon (blue) are regulated, whether they are orthologs (“Regulated exon orthologs (R-conservation)”) or not (“Regulated non-ortholog exons”). b Number of Nova-dependent exons in mouse and fruitfly as identified by vast-tools (ps: pasilla, drosophila homolog of mouse Nova1 and Nova2). c Output of the compare_exons_sets module when run on mouse (query) and fruitfly (target) Nova-regulated exon sets presented in b. The table reports the conservation statistics at the gene level, while the barplot represents the conservation statistics at the exon level (with colors referring to the scenarios depicted in a)