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Fig. 4 | Genome Biology

Fig. 4

From: ExOrthist: a tool to infer exon orthologies at any evolutionary distance

Fig. 4

ExOrthist paralogy inference in the Xenopus genus. a Scheme depicting the most common fates for the X. laevis (Xla) paralogs (genes and exons) generated by a whole genome duplication (WGD) occurred 31 million years after the split between Xla and X. tropicalis (Xtr) [36]. Each copy of a paralogous gene pair belongs to a different subgenome (S or L). Both gene paralogs can be conserved, giving rise to 1:2 orthologs (Xtr:Xla). Alternatively, one gene copy can be lost (either from the S or the L subgenome), re-establishing a 1:1 orthology relationship. The same classification is applied to paralogous exons in 1:2 gene orthologs. Ancestral exons may be conserved in both genes copies (1:2) or lost by either the S or L copy (1:1). b Percentages of 1:1 and 1:2 genes (red) or exons (blue) in the Xla genome, with the relative percentages of S and L alleles for the 1:1 genes/exons. Cases for which the L or S membership was not defined were excluded from the plot

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